Platelet satellitism and alpha granule proteins.
نویسندگان
چکیده
منابع مشابه
Platelet satellitism.
Platelet adherence to polymorphonuclear plasma m#{149}mbranes. Phagocytosis of leukocytes, or so-called platelet satellitplatelets was also observed. In vivo and ism, has, to our knowkdge, been reported in vitro platelet functions were normal. in only four patients. We had the opporPlatelet satellitism is an in vitro phenomtunity to study this phenomenon in two enon, the cause of which is unkno...
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Four platelet proteins are secreted by platelets during the release reaction: platelet factor 4 (PF4).1 $-thromboglobulin ( 9TG). platelet-derived growth factor (PDGF). and fibrinogen. The characteristics of release of these proteins and 14Cserotonin (14C-5HT) were studied and compared with secretion of acid hydrolases as described by others.’ Distinct differences were found between the release...
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DOI: 10.5581/1516-8484.20130060 Platelet satellitism is an in vitro phenomenon involving platelet rosetting around mature granulocytes that is observed exclusively in edetic acid (EDTA)-treated peripheral blood at room temperature(1). The precise underlying mechanism of platelet satellitism remains to be fully elucidated but the current explanations include an immunologic mechanism, characteriz...
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At sites of blood vessel injury, platelets release numerous substances that may have biological activities influencing cellular responses. In this study we examined separately the chemotactic activity for fibroblasts of three highly purified proteins obtained from platelet alpha granules: platelet factor 4 (PF4), platelet-derived growth factor (PDGF), and beta-thromboglobulin (BTG). We observed...
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Correspondence: Giuseppe Longo, Dipartimento di Scienze Mediche, Oncologiche e Radiologiche, Sezione di Medicina Interna, via Del Pozzo 71, 41100 Modena, Italy. Phone: international +39-059-422782 – Fax: international +39-059-424549 – E-mail: [email protected] aware that some thrombocytopenias of uncertain etiology may be artifactual in particular conditions; spurious thrombocytopenia due to EDTA-...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1991
ISSN: 0021-9746
DOI: 10.1136/jcp.44.9.788